A 3D human whole-body model with integrated organs vasculature musculoskeletal and nervous systems for mapping nerves

Study Purpose: The goal of this work is to create an annotated human whole-body scaffold with embedded organs, musculoskeletal, vasculature, and nervous systems.

Data Collection: The generic scaffold is created based on the generic body coordinates that fit data for the human whole-body. The generated organ scaffolds were embedded by embedding the fiducial markers. The fiducials for the nerves are placed by best guess into the human body using literature to check and verify the location. The muscles and bones are fitted to data. Additionally, the data for the vasculature system was obtained from Anatomography. An automated workflow was developed to obtain the central path of the vessels. The algorithm calculates the radius for each vessel, and then cubic Hermite splines are fitted to the central paths using least-square minimization to achieve smooth and continuous curves.

Primary Conclusion: None stated

Curator’s Notes

Experimental Design: Not applicable.

Completeness: The study is ongoing and potentially will link to other datasets where the data is used for mapping onto the scaffold.

Subjects & Samples: The body scaffold is not subject/sample-specific, but the morphed scaffold was fitted to the given data.

Primary vs derivative data: In the primary folder, nodal information and element connectivity of the scaffold are formatted as an exf file. Using the commands in the CMGUI file, the scaffold can be visualized using the open-source software CMGUI. The primary folder also contains a JSON file that contains MAP-Client workflow to reproduce the files. The derivative folder contains JSON files that are used to generate a visualization of the scaffold on the web portal.

Code Availability: https://github.com/ABI-Software/scaffoldmaker (ABI-Software/scaffoldmaker Anatomical scaffold generator using OpenCMISS), https://models.physiomeproject.org/workspace/add (scaffold source files)