We are developing a novel wireless device named Fecobionics for mapping colonic and anorectal neuromuscular function. The current dataset contains results from the Fecobionics test in the anorectal of human subjects with fecal incontinence.
The generated body scaffold was fitted to data, and the organ fiducial markers were embedded in the human whole-body. The landmarks were obtained from image data and also were defined in the body scaffold. Furthermore, nerve centrelines are added.
updated on May 17, 2023
musculoskeletal system, vasculature system, nervous system
Stellate ganglia of 15-16 week old Wistar and Spontaneously Hypertensive Rats were analyzed by: RNA-sequencing, differential analysis, and gene ontology analysis. Data were analyzed by a pipeline consisting of Salmon, DESeq2, and clusterprofiler.
NIH SPARC Program
updated on May 12, 2023
transcriptomics, differential expression, rna-sequencing
MicroCT imaging of the human cervical vagus nerve: slices at 0.5 cm spacing are provided across a 5 cm window representing the surgical window typical of vagus nerve stimulation. Derived data include fascicle morphometry, splitting and merging events.
A computational workflow for integration and implementation of a reusable and reproducible human cardiac multi-scale electrophysiology model.
Caption: Illustration of ion channels and action potential propogation in cardiac tissue
A computational workflow for integration and implementation of a reusable and reproducible rabbit cardiac multi-scale electrophysiology model.
Caption: Illustration of ion channels and action potential propogation in cardiac tissue.
Computational models and resulting activation thresholds of vagus nerve stimulation for simplified nerve morphologies, built with ASCENT v1.0.3. Modeled electrode designs include monopolar and clinical LivaNova helical cuffs.
updated on March 13, 2023
peripheral nerve stimulation, fascicle size, vagus nerve stimulation
Computational models and resulting activation thresholds of vagus nerve stimulation with the LivaNova helical cuff, built with ASCENT v1.1.1, using histology from nine human vagus nerves at the mid-cervical level.
updated on March 10, 2023
vagus nerve stimulation, peripheral nerve stimulation, computational modeling
Computational models of monopolar pig vagus nerve stimulation with a six-contact cuff, built with ASCENT v1.0.1, using the histology for six pigs in which electrophysiological outputs were recorded in vivo.
updated on March 9, 2023
vagus nerve, computational modeling, vagus nerve stimulation
A wired, active UroMOCA device was placed in the subject's bladder. The device was tested for its ability to transmit bladder pressure, conductivity, and conductance data from the device to a computer.