This dataset is about electrophysiological experiment on porcine colonic submucosal enteric neurons. The neurons were challenged with 2 different mechanical stimuli (compression and stretch). Neuronal responses to the stimuli were recorded and analyzed.
updated on June 4, 2021
mechanosensitivity, voltage sensitive dye, ultrafast neuroimaging technique
The generated body scaffold was fitted to data and the organ fiducial markers were embedded in the rat whole-body. The landmarks were obtained from image data and also were defined in the body scaffold.
Direct proximal colon, transverse colon and colorectum wall electrical stimulation; monitor colon wall bio-impedance and colon manometry in all regions (proximal, transverse and distal) before, during and post stimulation.
Animal study (C57BL/6J background transgenic mice) to determine the involvement of the superior mesenteric ganglion in the cholinergic anti-inflammatory pathway using optogenetic activation or blockade.
Stellate ganglia of 15-16 week old Wistar and Spontaneously Hypertensive Rats were analyzed by: RNA-sequencing, differential analysis, and gene ontology analysis. Data were analyzed by a pipeline consisting of Salmon, DESeq2, and clusterprofiler.
updated on May 13, 2021
differential expression, rna-sequencing, stellate ganglia
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