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Triaxial mechanical testing of dog colon segments

Measurement data related to the mechanical testing of dog colon samples under triaxial (inflation, extension, torsion) loading.
46 Files
3.1 MB
29 Records
CC-BY-4.0
Dataset will be released on September 1, 2021
force, inflation, pressure + More
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Test case for physiological data visualisation

Database to test out file requirements for time series visualisation
22 Files
31.05 MB
No Records
CC-BY-4.0
Mabelle Lin updated on May 14, 2021
physiological data, time series
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TRAP-SEQ (Translating Ribosome Affinity Purification followed by RNA sequencing) of iBAT-related ganglia from 7-day cold and warm treated mice

Molecular-genetic techniques in the autonomic nervous system: Projection-specific tracing and ribosomal RNA pulldown
51 Files
22.68 GB
13 Records
CC-BY-4.0
Heike Muenzberg updated on May 13, 2021
gene expression, ganglion, cold treatment + More
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RNA sequencing reveals novel transcripts from sympathetic stellate ganglia during cardiac sympathetic hyperactivity in rats

Stellate ganglia of 15-16 week old Wistar and Spontaneously Hypertensive Rats were analyzed by: RNA-sequencing, differential analysis, and gene ontology analysis. Data were analyzed by a pipeline consisting of Salmon, DESeq2, and clusterprofiler.
27 Files
3.3 MB
25 Records
CC-BY-4.0
scott john updated on May 13, 2021
differential expression, rna-sequencing, stellate ganglia + More
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Tool for uploading files to Blackfynn

Upload_bfynn aids with file uploads to Blackfynn. Users create a csv file with folders and names that meet the BIDS-like standards and lists the sources of files to be uploaded into these folders. Local filenames and folder structures are not changed.
100 Files
37.14 MB
6 Records
GPL-3.0
Kendall Morris updated on May 12, 2021
software, neural circuits, spike trains + More
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Acquisition of single neurons and regional neuronal samples from the porcine Right Atrial Ganglionic Plexus (RAGP) through Laser Capture Microdissection

Transcriptional Diversity of Single Neurons in the Porcine RAGP.High throughput qPCR data for over 400 single neurons assayed for hundreds of genes across 4 pig RAGP
11,073 Files
7.32 GB
2 Records
CC-BY-4.0
Alison Moss updated on May 14, 2021
sparc, ragp, lcm + More
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Generic rat stomach scaffold

Annotated rat stomach scaffold available for registration of segmented neural anatomical-functional mapping of enteric neural circuits.
38 Files
5.66 MB
6 Records
CC-BY-4.0
Mabelle Lin updated on May 10, 2021
myenteric plexus, stomach, rat
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Generic human stomach scaffold

Annotated human stomach scaffold available for registration of segmented neural anatomical-functional mapping of enteric neural circuits.
28 Files
5.21 MB
No Records
CC-BY-4.0
Mabelle Lin updated on May 10, 2021
stomach, human, myenteric plexus
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Computational analysis of the human sinus node action potential - Model development and effects of mutations

CellML version of the Fabbri et al. 2017 model
16 Files
149.05 KB
4 Records
CC-BY-4.0
Alan Garny updated on May 10, 2021
cardiovascular models, ion channels, sinoatrial node + More
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Human whole-body scaffold

Annotated human whole-body scaffold (abdomen, diaphragm, thorax, neck, head, skin, spinal cord) with embedded vagus nerves.
30 Files
8.87 MB
No Records
CC-BY-4.0
Elias Soltani updated on May 7, 2021
whole-body, human, torso + More
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Retrograde tracing of interscapular brown adipose tissue (iBAT) specific sympathetic neurons in mice - virus and reporter testing

Document and analyze the efficiency of retrograde viral transport amongst different viral constructs and mouse models
21 Files
268.47 KB
6 Records
CC-BY-4.0
Heike Muenzberg updated on May 7, 2021
cav2, ibat, sympathetic chain ganglia + More
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Acute wired Urological Monitor of Conscious Activity (UroMOCA) implantation in feline bladder

Testing of a bladder sensor device
849 Files
1.31 GB
16 Records
CC-BY-4.0
Dataset will be released on July 1, 2021
cat, uromoca, urodynamics + More
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Gene expression profile of interscapular brown adipose tissue (iBAT) and inguinal white adipose tissue (iWAT) whole ganglia sequencing in mice

Identification of the gene expression profile of interscapular brown fat (iBAT)-related ganglia (SG/T1 & T3) and inguinal white fat (iWAT)-related ganglia (T13/L1 & L2).
65 Files
19.16 GB
55 Records
CC-BY-4.0
Heike Muenzberg updated on May 5, 2021
inguinal white fat (iwat), l2, gene expression + More
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Acute wired ColoMOCA implantation in pig bowel

Testing of wired bowel sensor devices
73 Files
12.21 MB
17 Records
CC-BY-4.0
Dataset will be released on July 1, 2021
wireless, pig, colomoca + More
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Functional mapping with lumbosacral epidural stimulation for restoration of bladder function after spinal cord injury in rats

Animal study to determine the electrode configurations that promote functional gains in the storage and voiding phases of lower urinary tract function as a result of activation of spinal circuits with spinal cord epidural stimulation in injured spine.
66 Files
54.86 GB
99 Records
CC-BY-4.0
Fahmi Khalifa updated on May 3, 2021
epidural stimulation, urogenital, bladder + More
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Chemogenetic whole-body and iBAT (interscapular brown adipose tissue) -specific sympathetic stimulation in anesthetized mice

Functional effects of whole-body and iBAT-specific stimulation while under acute anesthesia
21 Files
326.29 KB
6 Records
CC-BY-4.0
Heike Muenzberg updated on April 12, 2021
aav, sympathetic, chemogenetics + More
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Chemogenetic iBAT (interscapular brown adipose tissue)-specific sympathetic stimulation and e-mitter implant in mice

Chemogenetic iBAT-specific sympathetic stimulation and e-mitter implant
33 Files
1.24 MB
16 Records
CC-BY-4.0
Heike Muenzberg updated on April 12, 2021
thermogenesis, sympathetic, ibat + More
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Optogenetic activation of nitrergic and cholinergic neurons of murine colonic myenteric plexus

Tension recordings of proximal, middle and distal colon after optogenetic activation of nitrergic and cholinergic myenteric neurons
46 Files
138.27 MB
31 Records
CC-BY-4.0
Dataset will be released on May 31, 2021
myenteric plexus, cholinergic, nitrergic + More
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Characterization of projections of longitudinal muscle motor neurons in human colon

DiI-retrograde tracing ex vivo plus immunohistochemistry to characterise Longitudinal muscle motor neurons
1,736 Files
3.05 GB
73 Records
CC-BY-4.0
Simon Brookes updated on April 11, 2021
smooth muscle, motor neuron, human + More
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In Vitro Imaging of Mechanosensitive Submucous Neurons in the Porcine Colon

This dataset is about electrophysiological experiment on porcine colonic submucosal enteric neurons. The neurons were challenged with 2 different mechanical stimuli (compression and stretch). Neuronal responses to the stimuli were recorded and analyzed.
73 Files
22.81 MB
115 Records
CC-BY-4.0
Gemma Mazzuoli-Weber updated on April 11, 2021
immunohistochemistry, voltage sensitive dye, ultrafast neuroimaging technique + More
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Functional mapping of the stomach neural circuitry - GES-evoked duodenal motility in rats is stimulation site dependent

Functional mapping of the stomach’s neural circuitry: GES-evoked duodenal motility in rats is stimulation site dependent.
181 Files
2.45 GB
237 Records
CC-BY-4.0
Terry Powley updated on April 11, 2021
mapping, motility, stomach + More
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MicroCT imaging of rat stomach vasculature with Microfil MV-122

The stomach vasculature was filled at perfusion with a lead-containing silicone-based curable fluid (Microfil MV-122). Once the contrast medium was cured, the stomach was removed and fixed and subsequently imaged via microCT.
203 Files
10.32 GB
67 Records
CC-BY-4.0
Terry Powley updated on April 11, 2021
micro-ct, stomach, vasculature + More
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Chronic wireless Urological Monitor of Conscious Activity (UroMOCA) implantation in feline bladder

Recording bladder function in ambulatory cats using an implanted, wireless device
3,258 Files
2.58 GB
24 Records
CC-BY-4.0
Margot Damaser updated on April 10, 2021
pressure, bladder, wireless + More
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Transcriptional Diversity of Single Neurons in the Porcine Right Atrial Ganglionic Plexus (RAGP)

Single neurons were collected from 4 different porcine RAGP through Laser Capture Microdissection (LCM) and subjected to HT-qPCR to assay for expression of over 200 genes.
3,667 Files
46.53 GB
431 Records
CC-BY-4.0
Alison Moss updated on April 10, 2021
ht-qpcr, single neurons, ragp
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Spatially Tracked Single-Neuron Transcriptomics of a Male Porcine Right Atrial Ganglionic Plexus (RAGP)

Single neurons and regional neuronal samples were collected from a male porcine RAGP through Laser Capture Microdissection with preserved spatial tracking.
23 Files
125.37 MB
95 Records
CC-BY-4.0
Alison Moss updated on April 10, 2021
single neurons, spatial tracking, 3d ragp
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