Find and access public scientific datasets.

Deep phenotyping of Post-infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Transmission electron microscopy (TEM) images and segmentation of nerve fibers

Data for the manuscript titled "Utility of iEEG networks in modeling brain activity depends on re-referencing and connectivity choice"

We are developing a novel wireless device named Fecobionics for mapping colonic and anorectal neuromuscular function. The current dataset contains results from the Fecobionics test in the anorectal of human subjects with fecal incontinence.

Immunostaining and imaging of Cre reporter lines in mouse lung lobes

Images collected from serial cryostat sectioning of a cryopreserved heart was used to reconstruct the 3D context. Transcriptional profiles taken from isolated single neurons and mapped back into the previously generated 3D context.

Computational model of vagus nerve stimulation in mice with a bipolar cuff electrode, built with ASCENT v1.1.4, using a generalized nerve morphology.

Computational models and resulting activation thresholds of vagus nerve stimulation with the LivaNova helical cuff, built with ASCENT v1.1.1, using histology from nine human vagus nerves at the mid-cervical level.

Computational models of monopolar pig vagus nerve stimulation with a six-contact cuff, built with ASCENT v1.0.1, using the histology for six pigs in which electrophysiological outputs were recorded in vivo.

Validated computational models of rat (Micro-Leads Neuro, n=1), pig (LivaNova, n=20), and human (LivaNova, n=9) vagus nerve stimulation, built with ASCENT v1.1.1, using histology to define nerve morphologies, and using the cuff electrodes and waveforms

Quantification of serotonin release from intestinal organoids isolated from genetically modified mice.

We are developing a novel wireless device named Fecobionics for mapping colonic and anorectal neuromuscular function. The current dataset contains results from pilot Fecobionics tests in the anorectal of healthy human subjects.

We are developing a novel wireless device named Fecobionics for mapping colonic and anorectal neuromuscular function. The current dataset contains results from the Fecobionics tests in the anorectal of healthy human subjects.

This dataset maps the relationship between vagus nerve stimulation (VNS) parameters to their immediate neural and cardiac effects in 2 pigs under anaesthesia.

DiI-retrograde tracing ex vivo plus immunohistochemistry to characterise long ascending and descending myenteric neurons in human colon

This dataset displays the digitally traced spinal afferent axons and their terminal structures in flat-mounts of the whole rat stomach muscular wall using tracer Dextran Biotin injection into the left thoracic DRG T7-T11.

Synthetic and native direct RNA sequencing data

Processed Diffuse in vivo flow Cytometry and bench top Flow Cytometry data collected during the study of labeling L1210A leukemia cells in vivo with OTL38 and detecting them with NIR-DiFC

Immunostaining and imaging of Cre reporter lines in mouse lung lobes

A tutorial showing how to expand the SPARC Dataset Structure on oSPARC

This tutorial is designed to guide the users on how to modify data points for other applications, such as simulations

A python library to generate and interact with flatmaps in a jupyter notebook using the ipyleaflet library

Series of Jupyter notebook tutorials showing how to use sparc-me, a python tool to explore, enhance, and expand SPARC datasets and their descriptions in accordance with FAIR principles.

This model represents an evolved iteration of the original Simulink model that emulates the acute cardiac outcomes resulting from vagus nerve stimulation, as initially proposed by Haberbusch et al (see associated publications)

Distributions of enteroendocrine cells (EEC), defined by the hormones they contain within the human fundus and corpus are mapped onto the human stomach scaffold.