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Design and Validation of Near-Infared Diffuse In Vivo Flow Cytometry

This data set includes the data files relevant to the building and validating of a near-infrared diffuse in vivo flow cytometry instrument.
59 Files
2.26 GB
No Records
CDLA-Permissive-1.0
Josh Pace updated on August 16, 2022
diffuse fluorescence, near-infrared light, diffuse in vivo flow cytometry
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Correlated electrophysiological immunohistochemical and morphological properties of proximal colon myenteric neurons

Each set includes membrane potential records from a myenteric neuron of mouse proximal colon plus micrographs of cell body morphology, immunoreactivity for nNOS, calretinin (where possible), and micrographs showing axonal projections
2,532 Files
14.88 GB
258 Records
CC-BY-4.0
Marthe Howard updated on August 9, 2022
microscopy, electrophysiology, immunohistochemistry + More
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Effect of chronic gastric electrical stimulation on the feeding behavior of male rats consuming a 45% high-fat diet

Microstructural analysis of food intake as a behavioral endpoint to determine the effect of chronic gastric electrical stimulation on the consumption of a high fat diet by adult male Sprague-Dawley rats.
49 Files
1.86 MB
No Records
CDLA-Permissive-1.0
Robert Phillips updated on July 29, 2022
ges, sprague-dawley, rat + More
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Effects of vagal afferent blockade on gastric motility during cervical vagus nerve stimulation measured with magnetic resonance imaging in rats

This study aims to evaluate the effects of cervical VNS on gastric motility in rats. The aim is to selectively activate or block the afferent pathway to disentangle their differential effects on gastric responses.
174 Files
4.96 GB
29 Records
CC-BY-4.0
Zhongming Liu updated on July 29, 2022
stomach, vagus nerve stimulation, rat + More
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In vivo mapping of gastric electrical activation with manganese enhanced magnetic resonance imaging

We used MRI to map gastric electrical activation following meal consumption. Manganese ions were used as a surrogate of calcium ions to map the increase of calcium influx, presumably into smooth muscle cells.
28 Files
53.76 MB
20 Records
CC-BY-4.0
Zhongming Liu updated on July 28, 2022
manganese-enhanced mri, gastric electrical activation, rat + More
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Effects of vagal efferent blockade on gastric motility and emptying during cervical vagus nerve stimulation measured with magnetic resonance imaging in rats

This study aims to evaluate the effects of cervical VNS on gastric emptying and motility in rats.
695 Files
4.2 GB
25 Records
CC-BY-4.0
Zhongming Liu updated on July 27, 2022
stomach, efferent blockade, vagus nerve stimulation + More
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Effect of chronic gastric electrical stimulation on the feeding behavior of female rats consuming a 45% high-fat diet

Microstructural analysis of food intake was used as a behavioral endpoint to determine the effect of chronic gastric electrical stimulation on the consumption of a 45% high fat diet by adult female Sprague-Dawley rats.
56 Files
1.71 MB
No Records
CDLA-Permissive-1.0
Robert Phillips updated on July 26, 2022
ges, sprague-dawley rats, high fat diet
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Acute effects of gastric electrical stimulation settings on neural activity in the nucleus of solitary tract in rats

This study aims to evaluate the effects of GES settings on neural activity in rats NTS. Briefly, multi-unit activity is recorded in the nucleus of the solitary tract in rats.
1,424 Files
395.38 GB
22 Records
CC-BY-4.0
Zhongming Liu updated on July 22, 2022
nucleus of solitary tract, neural activity, rat + More
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Central terminal fields of lower urinary tract afferents in rat

Comprehensive mapping of lower urinary tract afferent projections within the lumbosacral spinal cord of male and female rats, using 3D reconstruction of sectioned cord (TissueMaker) and cleared intact cord (iDisco, light sheet microscopy).
90 Files
333.42 GB
55 Records
CC-BY-4.0
Janet Keast updated on July 21, 2022
visceral afferent, motoneuron, tissue clearing + More
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Scaffold map - Influence of direct colon tissue electrical stimulation on colonic motility in anesthetized male Yucatan minipig

Time series manometry data derived from direct proximal colon, transverse colon and distal wall electrical stimulation in the original dataset are mapped onto the pig colon scaffold.
45 Files
467.17 MB
No Records
CC-BY-4.0
Mabelle Lin updated on July 15, 2022
scaffold, motility, time series + More
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Expression of molecular markers in subpopulations of mouse superior cervical ganglion neurons

Expression of molecular markers in subpopulations of mouse superior cervical ganglion neurons using small molecule FISH (RNAScope)
157 Files
403.23 MB
41 Records
CC-BY-4.0
Lori Zeltser updated on July 26, 2022
smfish, sympathetic, rnascope + More
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Expression of molecular markers in subpopulations of mouse celiac ganglion neurons

Expression of molecular markers in subpopulations of mouse celiac ganglion neurons using small molecule FISH (RNAScope)
137 Files
355.82 MB
45 Records
CC-BY-4.0
Lori Zeltser updated on July 26, 2022
sympathetic, rnascope, celiac ganglion + More
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Optical mapping of action potentials and calcium transients in the mouse heart during optogenetic stimulation of the intracardiac ganglia and interconnecting neurons (ICNS)

Optical maps describing electrical propagation across the atria and ventricles before and after stimulation of intrinsic cardiac ganglionated plexi in the mouse heart
40 Files
95.46 MB
27 Records
CDLA-Permissive-1.0
Jeffrey Ardell updated on July 14, 2022
optical mapping, electrophysiology, parasympathetic + More
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Single cell RNA sequencing of retrogradely labeled mouse stellate ganglion neurons

Datasets from single cell sequencing of murine stellate ganglion neurons retrogradely labeled with cholera toxin B injections into the brown adipose tissue or forelimb
198 Files
154.49 GB
1,057 Records
CC-BY-4.0
Lori Zeltser updated on July 26, 2022
sympathetic, mouse, rna-seq + More
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Electrode design characterization for electrophysiology from swine peripheral nervous system

Comparison of cuff, microelectrode, and intrafascicular electrode to make evoked compound action potential (ECAP) and naturally occurring activity recordings from the peripheral nervous system. Dataset from pigs (n=3) - a human-scale large animal model.
722 Files
29.63 GB
16 Records
CC-BY-4.0
Kip Ludwig updated on July 14, 2022
electrode design, electrophysiology, vagus nerve stimulation
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Expression of molecular markers in subpopulations of mouse stellate ganglion neurons

Expression of molecular markers in subpopulations of mouse stellate ganglion neurons using single molecule FISH (RNAScope)
166 Files
466.31 MB
42 Records
CC-BY-4.0
Lori Zeltser updated on July 26, 2022
smfish, stellate ganglia, rnascope + More
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Expression of molecular markers in mouse and human stellate ganglia

We used immunohistochemistry to visualize the expression of molecular markers in stellate ganglia from mice and human. Data consist of images (CZI format) of SG cryosections stained with antibodies combinations, acquired with a Zeiss 710 microscope.
43 Files
438.09 MB
18 Records
CC-BY-4.0
Lori Zeltser updated on July 26, 2022
sympathetic, immunohistochemistry, stellate ganglion
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Rat whole-body with embedded organs using automatic workflow for inserting the organs

This dataset includes lung, bladder, heart, stomach and brainstem inserted into the rat whole-body using an automated workflow.
53 Files
45.39 MB
10 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Elias Soltani updated on July 13, 2022
embed, lungs, stomach + More
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Rat whole-body with embedded organs

The generated body scaffold was fitted to data and the organ fiducial markers were embedded in the rat whole-body. The landmarks were obtained from image data and also were defined in the body scaffold.
54 Files
23.5 MB
10 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Elias Soltani updated on July 13, 2022
embed, lungs, stomach + More
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Rat whole-body scaffold

Annotated rat whole body scaffold (abdomen, diaphragm, thorax, neck, head, skin, spinal cord) with embedded vagus nerves.
42 Files
9.18 MB
10 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Elias Soltani updated on July 13, 2022
whole body, rat, abdomen + More
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Pig whole-body with embedded organs using automatic workflow for inserting the organs

This dataset includes lung and heart inserted into the pig whole-body using an automated workflow.
33 Files
10.58 MB
10 Records
CC-BY-4.0
Elias Soltani updated on July 13, 2022
embed, lungs, heart + More
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Mouse whole-body with embedded organs

The generated body scaffold was fitted to data and the organ fiducial markers were embedded in the mouse whole-body. The landmarks were obtained from segmenting MRI data and also were defined in the body scaffold.
53 Files
22.57 MB
9 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Elias Soltani updated on July 13, 2022
embed, lungs, stomach + More
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4D upper gastrointestinal magnetic resonance imaging in healthy human subjects and gastroparetic patients

This aims to characterize gastric motility and emptying patterns in healthy human subjects and gastroparetic patients by using 4D contrast-enhanced MRI.
1,999 Files
667.53 GB
67 Records
CC-BY-4.0
Dataset will be released on February 15, 2023
gastroparesis, gastric mri, human + More
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Increased arrhythmia susceptibility in type 2 diabetic mice related to dysregulation of ventricular sympathetic innervation

Partial dataset from published manuscript of same title. Dataset includes intracellular recordings from control and diabetic mouse intrinsic cardiac neurons and stellate ganglion neurons.
422 Files
641.48 MB
24 Records
CC-BY-4.0
John Tompkins updated on July 12, 2022
stellate ganglion, type 2 diabetic, intrinsic cardiac neuron + More
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Substance P-immunoreactive axon innervation of mouse stomach

Immunohistochemistry revealed the morphology and distribution of nociceptor Substance P-immunoreactive (SP-IR) axons and terminals in the muscular layers (longitudinal muscle, myenteric plexus, and circular muscle) of the mouse stomach.
64 Files
2.51 GB
30 Records
CC-BY-4.0
Duyen Nguyen updated on July 12, 2022
longitudinal and circular muscles, nociceptive afferents, confocal microscopy + More
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