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Single cell RNA sequencing (scRNAseq) analysis identifies the cell populations in the muscularis externa of the pig colon

Single cell RNA sequencing of the pig colon
77 Files
43.41 GB
16 Records
CC-BY-4.0
Pu-Qing Yuan updated on July 16, 2021
transcriptomic analysis, pig colon, single cell rna sequencing + More
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Sympathetic and parasympathetic effects on subcellular cAMP responses in isolated ventricular myocytes

Measurement of compartmentalized cAMP responses to beta-adrenergic and muscarinic stimulation using FRET-based biosensors.
140 Files
11.9 GB
171 Records
CC-BY-4.0
Robert Harvey updated on July 16, 2021
lipid-rafts, camp, beta-adrenergic + More
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Antibodies tested in the colon – Mouse

List of antibodies that were tested in the mouse colon. Information on source, species, dilution, and whether the test was performed on whole colonic wall with CLARITY, or whole mount preparations of submucusal and myenteric plexus.
341 Files
22.43 GB
50 Records
CC-BY-4.0
Lixin Wang updated on July 16, 2021
antibody, colon
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Jupyterlab Exploration of Computational Models of Unmyelinated Peripheral Axons

Example JupyterLab environment used to compile, run and display results of neural computational models, based on a SPARC dataset (https://doi.org/10.26275/iiwv-k07f)
6 Files
25.48 KB
No Records
MIT
Katie Zhuang updated on July 8, 2021
jupyterlab, neuron, computational model + More
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Fabbri-based composite SAN model

CellML version of the Fabbri et al. 2017 human sinoatrial node (SAN) cell model and an ODE-based version of the Gerstner & Kistler 2002 brain stem model combined to demonstrate the effect of brain stem activity on heart rate
6 Files
116.7 KB
No Records
CC-BY-4.0
Alan Garny updated on July 7, 2021
cardiac electrophysiology, cardiovascular models, human + More
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Human whole-body with embedded organs

The generated body scaffold was fitted to data and the organ fiducial markers were embedded in the human whole-body. The landmarks were obtained from image data and also were defined in the body scaffold.
41 Files
52.26 MB
No Records
CC-BY-4.0
Elias Soltani updated on June 29, 2021
colon, heart, organ + More
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Generic rat heart scaffold

Annotated heart scaffold for rat available for registration of segmented neural anatomical-functional mapping of cardiac neural circuits.
42 Files
4.94 MB
5 Records
CC-BY-4.0
Richard Christie updated on June 29, 2021
ventricles, coronary, rat + More
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Generic rat brainstem scaffold

Annotated rat brainstem scaffold available for registration of segmented neural anatomical-functional mapping of neural circuits.
26 Files
3.36 MB
No Records
CC-BY-4.0
Arti Sukasem updated on June 29, 2021
brainstem, rat, scaffold
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Generic pig colon scaffold

Annotated pig colon scaffold available for registration of segmented neural anatomical-functional mapping of enteric neural circuits.
32 Files
66.47 MB
6 Records
CC-BY-4.0
Mabelle Lin updated on June 29, 2021
tenia coli, transverse colon, spiral colon + More
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Generic human heart scaffold

Annotated heart scaffold for human available for registration of segmented neural anatomical-functional mapping of cardiac neural circuits.
41 Files
5.59 MB
5 Records
CC-BY-4.0
Richard Christie updated on June 29, 2021
atria, ventricles, heart + More
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Generic human brainstem scaffold

Annotated human brainstem scaffold available for registration of segmented neural anatomical-functional mapping of neural circuits.
25 Files
3.34 MB
No Records
CC-BY-4.0
Arti Sukasem updated on June 29, 2021
brainstem, human, scaffold
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Optogenetic iBAT (interscapular brown adipose tissue) stimulation in anesthetized mice

Functional sympathetic iBAT stimulation
22 Files
232.77 KB
7 Records
CC-BY-4.0
Heike Muenzberg updated on June 29, 2021
sympathetic, thermogenesis, aav + More
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Sympathetic iBAT (interscapular brown adipose tissue) activation high fat (HF) low fat (LF) diet study

In this study we tested, if chemogenetic activation of BAT-specific sympathetic fibers causes beneficial metabolic effects on body weight, adiposity, glucose homeostasis and substrate flux in lean vs. obese mice.
26 Files
13.75 MB
65 Records
CC-BY-4.0
Heike Muenzberg updated on June 29, 2021
brown adipose tissue, low fat diet, aav6-cre + More
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Lower urinary tract nerve responses to high-density epidural sacral spinal cord stimulation

This dataset contains recordings of compound nerve action potentials from the pelvic nerve as well as the pudendal nerves and its branches in response to electrical stimulation on the epidural surface of the sacral spinal cord in anesthetized cats.
42,400 Files
925.41 GB
16 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Robert Gaunt updated on June 29, 2021
electrical stimulation, urethra, spinal cord stimulation + More
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Phrenic Nerve Stimulation Spinal Intact Rats

We are testing the hypothesis that activation of phrenic afferent neurons modulates contralateral phrenic motor output and blood pressure in the adult rat.
99 Files
93.7 GB
47 Records
CC-BY-4.0
David Fuller updated on June 15, 2021
phrenic motor output, phrenic nerve, respiratory bursting + More
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Influence of acute celiac branch of abdominal vagus nerve stimulation on colonic motility in anesthetized male Yucatan minipigs

Acute celiac branch of vagus nerve electrical stimulation; monitor colon manometry in all regions (proximal, transverse and distal) before, during and post stimulation.
206 Files
1.56 GB
45 Records
CC-BY-4.0
Muriel Larauche updated on June 14, 2021
pre-clinical, pelvic, electroceutical-therapy + More
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Influence of acute thoracolumbar root nerves electrical stimulation on colonic motility in anesthetized male Yucatan minipigs

Acute thoracolumbar nerve electrical stimulation; monitor colon manometry in all regions (proximal, transverse and distal) before, during and post stimulation.
87 Files
210.71 MB
20 Records
CC-BY-4.0
Muriel Larauche updated on June 14, 2021
pre-clinical, pelvic, electroceutical-therapy + More
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Generic pig heart scaffold

Annotated heart scaffold for pig available for registration of segmented neural anatomical-functional mapping of cardiac neural circuits.
41 Files
5.06 MB
5 Records
CC-BY-4.0
Richard Christie updated on June 9, 2021
coronary, pig, cardiac zone + More
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In Vitro Imaging of Mechanosensitive Submucous Neurons in the Porcine Colon

This dataset is about electrophysiological experiment on porcine colonic submucosal enteric neurons. The neurons were challenged with 2 different mechanical stimuli (compression and stretch). Neuronal responses to the stimuli were recorded and analyzed.
73 Files
22.81 MB
115 Records
CC-BY-4.0
Gemma Mazzuoli-Weber updated on June 4, 2021
mechanosensitivity, voltage sensitive dye, ultrafast neuroimaging technique + More
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Chemogenetic Activation or Inhibition of Cholinergic or Nitrergic Myenteric Neurons of Mouse Colon

Contractile response to the chemogenetic activation or inhibition of distinct myenteric neuronal subsets
61 Files
166.81 MB
No Records
CC-BY-4.0
Thomas Gould updated on June 3, 2021
optogenetics, myenteric plexus, motility + More
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Rat whole-body with embedded organs

The generated body scaffold was fitted to data and the organ fiducial markers were embedded in the rat whole-body. The landmarks were obtained from image data and also were defined in the body scaffold.
40 Files
23.46 MB
No Records
CC-BY-4.0
Elias Soltani updated on June 2, 2021
rat, abdomen, diaphragm + More
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Generic rat lung scaffold

Annotated lung scaffold for rat available for registration of segmented neural anatomical-functional mapping of pulmonary neural circuits.
29 Files
2.71 MB
No Records
CC-BY-4.0
Arti Sukasem updated on June 2, 2021
lung, rat, scaffold
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Generic rat bladder scaffold

Annotated bladder scaffold for rat available for registration of segmented neural anatomical-functional mapping of LUT neural circuits.
34 Files
2.36 MB
5 Records
CC-BY-4.0
Zohreh Ekhlasi updated on June 2, 2021
urinary bladder, urethra, body of the bladder + More
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Generic mouse lung scaffold

Annotated lung scaffold for mouse available for registration of segmented neural anatomical-functional mapping of pulmonary neural circuits.
37 Files
2.69 MB
5 Records
CC-BY-4.0
Arti Sukasem updated on June 2, 2021
lung, mouse
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Generic human lung scaffold

Annotated lung scaffold for human available for registration of segmented neural anatomical-functional mapping of pulmonary neural circuits.
37 Files
2.44 MB
5 Records
CC-BY-4.0
Arti Sukasem updated on June 2, 2021
lung, human
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