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Acute wired Urological Monitor of Conscious Activity (UroMOCA) implantation in feline bladder

A wired, active UroMOCA device was placed in the subject's bladder. The device was tested for its ability to transmit bladder pressure, conductivity, and conductance data from the device to a computer.
868 Files
1.31 GB
14 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Margot Damaser updated on January 18, 2022
urodynamics, bladder pressure, wireless + More
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Effect of electrical stimulation of vagal afferent terminals located in the stomach muscle wall on feeding behavior

Microstructural analysis of food intake as a behavioral endpoint to determine the efficacy of properly placed, optimally tuned gastric electrodes.
54 Files
25.57 MB
34 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Robert Phillips updated on January 6, 2022
vagus nerve, rat, stimulation + More
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Sympathetic nerve stimulation of mouse and rabbit hearts

We combined experiments and computational modeling to investigate the effects of sympathetic nerve stimulation on mouse and rabbit hearts.
58 Files
3.49 MB
6 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Stefano Morotti updated on January 5, 2022
sympathetic nerve stimulation, fight-or-flight response, cardiac electrophysiology + More
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Acute Wired Colonic Monitor of Conscious Activity (ColoMOCA) implantation in pig bowel

Testing of wired bowel sensor devices
121 Files
15.26 MB
15 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Margot Damaser updated on January 19, 2022
colomoca, bowel, pig + More
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Acute effects of vagus nerve stimulation (VNS) settings on neural activity in the nucleus of solitary tract (NTS) in rats

This study aims to evaluate the effects of VNS settings on neural activity in rats NTS.
1,152 Files
267.19 GB
16 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Zhongming Liu updated on January 4, 2022
nucleus of solitary tract, rat, neural activity + More
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Jupyterlab exploration of computational models of unmyelinated peripheral axons

Example JupyterLab environment used to compile, run and display results of neural computational models, based on a SPARC dataset (https://doi.org/10.26275/iiwv-k07f)
20 Files
27.17 MB
4 Records
MIT

Sponsored by

NIH SPARC Program

Katie Zhuang updated on January 4, 2022
peripheral, jupyterlab, neuron + More
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Acute effects of efferent and afferent vagus nerve stimulation (VNS) on neural activity accessed with functional magnetic resonance imaging (fMRI) in rats

This study aims to evaluate the effects of efferent/afferent VNS on neural activity in rats.
232 Files
18.3 GB
27 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Zhongming Liu updated on January 4, 2022
rat, neural activity, fmri + More
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Acute effects of gastric electrical stimulation settings on gastric motility assessed with magnetic resonance imaging in rats

This study aims to evaluate the effects of GES settings on gastric motility in rats.
57 Files
2.13 GB
15 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Zhongming Liu updated on January 3, 2022
rat, gastric motility, gastric electrical stimulation + More
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Quantitative analysis of enteric neurons containing choline acetyltransferase and nitric oxide synthase immunoreactivities in the submucosal and myenteric plexuses of the porcine colon

Quantitative study assessing choline acetyltransferase and nitric oxide synthase immunoreactivities in the submucosal and myenteric plexuses of the porcine colon. Regions of the porcine colon analyzed were ascending and descending colon.
587 Files
193.15 GB
61 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Catia Sternini updated on January 3, 2022
excitatory motor neurons, secretomotor neurons, inhibitory motor neurons + More
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Transcriptomic and neurochemical analysis of the stellate ganglia in mice highlights sex differences

This dataset contains baseline measurements of mouse stellate ganglia using RNAseq
36 Files
28.86 MB
34 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Jeffrey Ardell updated on December 15, 2021
sparc, transcriptome, sympathetic + More
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ViNERS (Visceral Nerve Ensemble Recording & Stimulation) peripheral neural interface modeling environment

ViNERS (Visceral Nerve Ensemble Recording & Stimulation) is a MATLAB-based neural interface modeling pipeline for modeling peripheral neural interface stimulation and recording performance for individual axons and whole-nerve ensembles.
238 Files
5.16 MB
6 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Janet Keast updated on December 15, 2021
autonomic nervous system, electrophysiology, finite element method + More
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RNA sequencing reveals novel transcripts from sympathetic stellate ganglia during cardiac sympathetic hyperactivity in rats

Stellate ganglia of 15-16 week old Wistar and Spontaneously Hypertensive Rats were analyzed by: RNA-sequencing, differential analysis, and gene ontology analysis. Data were analyzed by a pipeline consisting of Salmon, DESeq2, and clusterprofiler.
29 Files
3.52 MB
25 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Jeffrey Ardell updated on December 15, 2021
differential expression, stellate ganglia, rna-sequencing + More
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Cardioneural recordings

Methodology of neural recordings using array electrodes. How to analyze for signal to noise, spike sorting, and higher-level analysis.
67 Files
1.64 GB
36 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Jeffrey Ardell updated on December 15, 2021
pig, cardiac, microarray + More
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Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies part (2)

Data from the innervation of intact mice hearts and the mapping of parasympathetic and sympathetic neural circuits which control heart rate. This data set identifies the cholinergic and noradrenergic neurons which project to the sinoatrial node
397 Files
176.21 GB
76 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Jeffrey Ardell updated on December 15, 2021
noradrenergic, peripheral nervous system, cholinergic + More
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Recording of electrically evoked neural activity and bladder pressure responses in awake rats chronically implanted with a pelvic nerve array

Electrical neuromodulation of the rat pelvic nerve (homolog of the human pelvic splanchnic nerves) by chronically implanted custom planar four-electrode arrays and assessment of bladder pressure responses by cystometry in awake rats.
88 Files
44.9 MB
42 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Janet Keast updated on December 14, 2021
recording techniques, neural decoding, electrophysiology
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Safety testing of the Fecobionics device

We are developing a novel wireless device named Fecobionics for mapping colonic and anorectal neuromuscular function. The data of control device has been submitted. The current dataset contains results from the Fecobionics group of the safety study.
258 Files
2.14 GB
21 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Hans Gregersen updated on December 14, 2021
safety, gi, histology + More
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Identification of lung innervating sensory neurons and their target specificity in mouse (1)

Lightsheet imaging of mouse lung lobes
33 Files
163.18 GB
No Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Jamie Verheyden updated on December 16, 2021
mouse lung, lightsheet, innervation
Dataset Banner Image

Simulations of pelvic and vagus neural interface anatomy-dependent stimulus and recording properties

This is a dataset of simulations of planar neural interface stimulation and recording properties computed for single axons and neural ensembles using ViNERS, looking at the influence of fascicle size and perineurum thickness.
894 Files
15.16 GB
72 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Janet Keast updated on December 13, 2021
neural interfaces, autonomic nervous system, axon models + More
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Triaxial mechanical testing of dog colon segments

Measurement data related to the mechanical testing of dog colon samples under triaxial (inflation, extension, torsion) loading.
105 Files
7.17 MB
28 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Bhavesh Patel updated on December 9, 2021
force, pressure, extension + More
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Safety testing of predicate device for Fecobionics

We are developing a novel wireless device named Fecobionics for mapping colonic and anorectal neuromuscular function. This dataset contains results from the control group of the safety study.
256 Files
2.02 GB
19 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Hans Gregersen updated on December 8, 2021
safety, gi, histology + More
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Rat whole-body with embedded organs using automatic workflow for inserting the organs

This dataset includes lung, bladder, heart, stomach and brainstem inserted into the rat whole-body using an automated workflow.
50 Files
45.4 MB
6 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Elias Soltani updated on December 8, 2021
stomach, abdomen, head + More
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Acute effects of gastric electrical stimulation (GES) settings on neural activity accessed with functional magnetic resonance maging (fMRI) in rats

This study aims to evaluate the effects of GES on neural activity in rats, and exam, the role of the vagus nerve in the GES evoked neural activity.
868 Files
34.51 GB
24 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Zhongming Liu updated on December 1, 2021
rat, gastric electrical stimulation, ratus norvegicus + More
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An interactive system to visualize propagating vagal nerve activity in response to gastric electrical stimulation for gastroparesis

Created through BioCom Laboratory at Purdue University, this interactive GUI can be used to visualize electrode placement and propagating cervical vagus nerve activity tied to gastric electrical stimulation.
33 Files
4.68 MB
18 Records
Apache 2.0

Sponsored by

NIH SPARC Program

Matthew Ward updated on December 1, 2021
gastroparesis, vagus nerve, data visualization + More
Dataset Banner Image

Acute effects of efferent and afferent vagus nerve stimulation (VNS) on neural activity accessed with functional magnetic resonance imaging (fMRI) in rats (Part 2)

This study aims to evaluate the effects of efferent/afferent VNS settings on neural activity in rats. Functional Magnetic Resonance Imaging (fMRI) was performed to access the whole brain neural activity.
221 Files
16.22 GB
21 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Zhongming Liu updated on December 1, 2021
vagus nerve stimulation, neural activity, rat + More
Dataset Banner Image

Human whole-body with embedded organs using automatic workflow for inserting the organs

This dataset includes lung, bladder, heart, stomach and brainstem inserted into the human whole-body using an automated workflow.
42 Files
71.87 MB
No Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Elias Soltani updated on December 3, 2021
embed, bladder, human + More
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