Single neurons were mapped and cardiac anatomy was annotated in image volumes of male and female rat hearts to compare the intrinsic cardiac nervous system between individuals and across sexes.
92 Files
439.81 GB
50 Records
CC-BY-4.0
Sponsored by
NIH SPARC Program
Zixi Cheng
updated on March 22, 2023
rat intrinsic cardiac neurons, 3d heart reconstructions, rodent cardiac anatomy
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Computational models and resulting activation thresholds of vagus nerve stimulation for simplified nerve morphologies, built with ASCENT v1.0.3. Modeled electrode designs include monopolar and clinical LivaNova helical cuffs.
23,401 Files
676.03 MB
No Records
CC-BY-4.0
Nicole Pelot
updated on March 13, 2023
peripheral nerve stimulation, fascicle size, vagus nerve stimulation
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Computational models and resulting activation thresholds of vagus nerve stimulation with the LivaNova helical cuff, built with ASCENT v1.1.1, using histology from nine human vagus nerves at the mid-cervical level.
1,093 Files
655.22 MB
No Records
CC-BY-4.0
Eric Musselman
updated on March 10, 2023
vagus nerve stimulation, peripheral nerve stimulation, computational modeling
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The generated body scaffold was fitted to data, and the organ fiducial markers were embedded in the human whole-body. The landmarks were obtained from image data and also were defined in the body scaffold. Furthermore, nerve centrelines are added.
308 Files
116.91 MB
No Records
CC-BY-4.0
Elias Soltani
updated on February 28, 2023
musculoskeletal system, vasculature system, nervous system
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Computational models of monopolar pig vagus nerve stimulation with a six-contact cuff, built with ASCENT v1.0.1, using the histology for six pigs in which electrophysiological outputs were recorded in vivo.
6,419 Files
442.74 MB
19 Records
CC-BY-4.0
Eric Musselman
updated on March 9, 2023
vagus nerve, computational modeling, vagus nerve stimulation
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A wired, active UroMOCA device was placed in the subject's bladder. The device was tested for its ability to transmit bladder pressure, conductivity, and conductance data from the device to a computer.
Fixed samples of human atria and ventricles were sectioned and immunostained for neural markers using the ABC method. Specific targets were tyrosine hydroxylase, vesicular ACh transporter, and PGP9.5. Regional nerve densities were quantified using ImageJ.
This dataset includes GCaMP calcium imaging of myenteric neurons in the mouse proximal colon during spontaneous colon motor complexes (CMCs). Data were used in Nestor-Kalinoski et al, 2022: https://doi.org/10.1016/j.jcmgh.2021.08.016
26 Files
6.09 GB
14 Records
CC-BY-4.0
Kristen Smith-Edwards
updated on January 12, 2023
colon motor complex, mus sp., calcium imaging
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GCaMP recordings from thoracolumbar (T12 to L2) and lumbosacral (L5 to S1) DRG in responses to two chemical stimuli to the attached colorectum, i.e., acidic hypertonic solution (AHS) and inflammatory soup (IS).
Distributions of enteroendocrine cells (EEC), defined by the hormones they contain within the human fundus and corpus are mapped onto the human stomach scaffold.
This dataset contains the effects of abdominal vagus nerve stimulation on nodose ganglion cell activity recorded from multi-electrode arrays and gastrointestinal myoelectric responses recorded with serosal surface electrodes in the ferret.
Mapping of the vagal afferent innervation of the mouse lung using a combination of viral and genetic approaches to label unique vagal sensory subsets innervating the lung
Immunohistochemical analysis of the relationship between enteroendocrine cells and nerve endings in the gastric mucosa of human and pig. The innervation of mucosal vasculature is also revealed and current knowledge of the gastric innervation summarized.
Effect of electrical stimulation of the vagus nerve on colonic contractions and colonic neuron/ICC calcium activity, in ex vivo preparations lacking the targets of vagal afferent input.
44 Files
38.9 GB
48 Records
CC-BY-4.0
Thomas Gould
updated on January 3, 2023
calcium imaging, vagus nerve stimulation, colon
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