Computational model of laryngeal muscle activation in mice during vagus nerve stimulation

William Huffman, Ph.D.
,
Nicole A Pelot, Ph.D.
,
Warren M Grill, Ph.D.

Model of motor unit activation in laryngeal muscles.

Updated on March 9, 2023 (Version 1, Revision 1)

Corresponding Contributor:

Nicole Pelot
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Dataset Overview

Study Purpose: The purpose of this study is to replicate activation of laryngeal muscles in mice. The model was parameterized using particle swarm optimization algorithm.

Data Collection: Simulations were performed in MATLAB.

Data Conclusion: The model replicates in vivo findings including non-linear relationship with mean pulse rate.


Curator's Notes

Experimental Design: A computation model of laryngeal muscle activation in mice during vagus nerve stimulation.

Completeness: This dataset is complete.

Subjects & Samples: This is a computational model dataset; thus no subjects are described.

Primary vs derivative data: Not applicable. This is a computational study; the primary data folder contains MATLAB simulations of vagal activity.

Code Availability: Matlab script of the muscle activation model and the tonic pattern is provided in the code folder.

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About this dataset

Publishing history

March 2, 2023
Originally Published
March 9, 2023 (Version 1)
Last Updated

Cite this dataset

Huffman, W., Pelot, N. A., & Grill, W. M. (2023). Computational model of laryngeal muscle activation in mice during vagus nerve stimulation (Version 1) [Dataset]. SPARC Portal. https://doi.org/10.26275/E3N7-VEI4

References

Described by

Huffman, W. J., Musselman, E. D., Pelot, N. A., & Grill, W. M. (2023). Measuring and modeling the effects of vagus nerve stimulation on heart rate and laryngeal muscles. Bioelectronic Medicine, 9(1). https://doi.org/10.1186/s42234-023-00107-4