Scaffold map - Mapping of human gastric enteroendocrine cells

Mabelle Lin
,
Hugh Sorby
,
Peter Hunter

Distributions of enteroendocrine cells (EEC), defined by the hormones they contain within the human fundus and corpus are mapped onto the human stomach scaffold.

Updated on October 2, 2023 (Version 3)

Corresponding Contributor:

Mabelle Lin
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Dataset Overview

Study Purpose: The goal of this work is to map cell density data to an annotated generic human stomach scaffold.

Data Collection: The generic human stomach scaffold is created based on the general description and average dimensions of human stomachs. Cell density distribution data is collected by John Furness et al from the mucosal lining of the fundus and corpus regions of human stomachs. The data is derived from the original dataset.

Primary Conclusion: None stated


Curator's Notes

Experimental Design: Not applicable.

Completeness: Complete.

Subjects & Samples: This study used stomach tissue removed from 1 male adult and 3 female adult patients undergoing gastric sleeve surgery for obesity; stomach samples were derived from the fundus and antrum regions of the stomach.

Primary vs derivative data: The primary folder contains the mapping tool provenance data file needed to produce the scaffold map. The mapping tool will be accessible from the release download page on the SPARC Portal. The derivative folder contains webGL files which are used to generate a visualization of the scaffold map on the web portal.

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About this dataset

Publishing history

January 11, 2023
Originally Published
October 2, 2023 (Version 3)
Last Updated

Cite this dataset

Lin, M., Sorby, H., & Hunter, P. (2023). Scaffold map - Mapping of human gastric enteroendocrine cells (Version 3) [Dataset]. SPARC Portal. https://doi.org/10.26275/3VQO-XUX0

References

Derived from

Fakhry, J., Stebbing, M., Hunne, B., Bayguinov, Y., Ward, S. M., Sasse, K. C., Callaghan, B., McQuade, R. M., & Furness, J. (2020). Mapping of human gastric enteroendocrine cells (Version 1) [Data set]. SPARC Portal. https://doi.org/10.26275/PPGJ-QQPF

Lin, M., Christie, R., & Hunter, P. (2022). Generic human stomach scaffold (Version 4) [Data set]. SPARC Portal. https://doi.org/10.26275/D52I-YVES

Is Supplemented by

Scaffold Mapping Protocol - Version 1.1.1 v3. (2022). https://doi.org/10.17504/protocols.io.n2bvj6o35lk5/v3