4D upper gastrointestinal magnetic resonance imaging in healthy human subjects and gastroparetic patients

Kun-Han Lu
Kristine Mosier
Zhongming Liu
John Wo
Anita Gupta
Megan Jarrett
Travis Putzke
Deborah Jaffey, Ph.D.
Jiayue Cao
Xiaokai Wang
Bartek Rajwa
Terry L Powley, Ph.D.

This aims to characterize gastric motility and emptying patterns in healthy human subjects and gastroparetic patients by using 4D contrast-enhanced MRI.

Updated on July 13, 2022 (Version 1)

Corresponding Contributor:

Deborah Jaffey
Dataset Banner Image
1,999 Files
667.53 GB
67 Records

Dataset Overview

Study Purpose: The purpose of this study is to characterize other possible gastric dysfunctions in gastroparesis by using Cine magnetic resonance imaging (MRI) and elucidate the potential correlation between regional gastric motility parameters and symptom scores.

Data Collection: 3D and 4D MRI data was collected on both healthy volunteers and on gastroparetic patients before and after consuming a high contrast meal

Primary Conclusion: Multiple gastric motility parameters can be concurrently and quantitatively assessed by Cine MRI. Regional gastric abnormalities were found to be associated with patient symptoms. This study demonstrates that a fuller assessment of regional gastric functions in gastroparesis can improve the understanding of the relationship between gastric dysmotility and gastroparetic symptoms.

Curator's Notes

Experimental Design: This study aims to characterize gastric motility and emptying patterns in healthy human subjects and gastroparetic patients. Briefly, 4D gastric MRI scans were taken after subjects finished a caloric, nutritionally complete meal. Gastric volumes were segmented and reconstructed into 3D isosurfaces for the estimation of gastric motility. The frequency, amplitude, and coordination of peristaltic contraction waves could be computed from gastric wall movements. The data is taken from measurements on 27 healthy volunteers (11M/17F) and 19 gastroparetic patients (6M/13F).

Completeness: This dataset is complete.

Subjects & Samples: Male (n= 17) and female (n=30) human subjects were used in this study.

Primary vs derivative data: Primary data includes about 2500 files totaling about 670GB, comprising 3D and 4D NIFTI weighted gastric MRI data. The derivative folder contains segmented data and various measurements in Matlab format. In addition, an Excel spreadsheet of gastroparetic patient responses to a symptom assessment questionnaire is included.

Code Availability:The code folder contains the main source code (built under Windows 10 Matlab r2019a) related to Lu et al., 2021. Example datasets (human gastric MRI images) are provided along with the source code. The scripts are organized according to prefixes:

Global scripts: Path to root folder, parameters necessary for image processing, etc.

Amri scripts: Image processing scripts for main processing and sub-functions.

Tools scripts: functions for general purposes.


This dataset is currently under embargo. Files will be made publicly available on 02/15/2023.

No files found.

About this dataset

Publishing history

July 13, 2022
Originally Published
July 13, 2022 (Version 1)
Last Updated

Cite this dataset


Is Supplemented by

This dataset is under embargo and will be made publicly available on 02/15/2023