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Targeting bladder function with network-specific epidural stimulation after chronic spinal cord injury

This dataset contains measurements of the motor outcomes of the lower urinary tract in response to spinal cord epidural stimulation, utilizing electromyography of the external urinary sphincter and urodynamics.

48 Files

341.26 MB

No Records

Daniel Medina Aguinaga updated on April 19, 2024

bladder, spinal cord

Long read sequencing of human dorsal root ganglia

Long read sequencing was used to identify and characterize the isoforms expressed in the human dorsal root ganglion (hDRG). PacBio IsoSeq circular consensus sequencing was used on 3 hDRGs from 3 human organ donors.

22 Files

159.27 MB

No Records

Asta Arendt-Tranholm updated on April 6, 2024

long read sequencing, human, drg

Transcriptomic and neurochemical analysis of the stellate ganglia in mice highlights sex differences

This dataset contains baseline measurements of mouse stellate ganglia using RNAseq

38 Files

28.89 MB

44 Records

Jeffrey Ardell updated on March 19, 2024

sympathetic, transcriptome, neurotransmitters + More

Quantification of enteric ganglia in the three main regions of the rat stomach

This dataset contains images and analysis used to quantify the number of neurons per ganglia, size and density of myenteric and submucosal ganglia in the rat gastric fundus, corpus and antrum.

612 Files

445.24 GB

56 Records

Martin Stebbing updated on March 19, 2024

rat, ganglia, antrum + More

Vagal preganglionic axons arborize in myenteric plexus into two patterns generating nitrergic and non-nitrergic postganglionic motor units

The dataset consists of photomicrographs of the individual ganglia traversed by each of 54 vagal preganglionic fibers that had previously been fully traced using Neurolucida software.

2,566 Files

21.45 GB

103 Records

Deborah Jaffey updated on March 18, 2024

preganglionic, nitrergic, efferent + More

Vasculature in mouse colon and relationship with enteric nervous system glia and macrophages

This dataset contains microscopic images examining vascular structures in the mouse colon, yielding 3D images.

1,690 Files

88.5 GB

No Records

Lixin Wang updated on March 18, 2024

vessels, microvessels, capillaries + More

Light microscopic analysis of synaptic input to neurons in the rat major pelvic ganglion

High resolution 3D confocal images of autonomic neurons and closely opposing synaptic boutons were segmented and analysed to obtain statistics on preganglionic input to immunohistochemically classified lower urinary tract projecting MPG neurons.

6,264 Files

2.76 TB

6,528 Records

Janet Keast updated on March 18, 2024

synapse, 3d image analysis, autonomic ganglion + More

Transduction of systemically administered adeno-associated virus in the colonic enteric nervous system of adult mice

This dataset contains photomicrographs of the systemic AAV mouse colon enteric nervous system (ENS) that were acquired using confocal microscopes, visualized in three dimensions, and digitally segmented.

2,630 Files

93.5 GB

No Records

Lixin Wang updated on March 18, 2024

enteric nervous system, distribution, adeno-associated virus + More

Substance P-immunoreactive axons in the antrum-pylorus-duodenum of mice

Immunohistochemistry revealed the morphology and distribution of nociceptor substance P-immunoreactive (SP-IR) axons and terminals in the muscular, submucosal, and mucosal layers of the antrum, pylorus, and duodenum regions of the mice.

380 Files

70.98 GB

22 Records

Duyen Nguyen updated on March 18, 2024

substance p, nociceptive afferent, muscles + More

Excitation properties of computational models of unmyelinated peripheral axons

Data and plotting code for excitation responses of multiple single compartment and multi-compartment models of peripheral unmyelinated axons

1,971 Files

954.34 MB

15 Records

Nicole Pelot updated on February 26, 2024

autonomic nervous system, voltage-gated ion channels, vagus nerve + More

Intravenously injected AAV9 transduced interstitial cells of Cajal in mouse colon

AAV9-c-Kit mouse colon

461 Files

8.03 GB

No Records

Lixin Wang updated on March 20, 2024

interstitial cells of cajal, enteric nervous system, aav9 + More

Calcitonin gene-related peptide - immunoreactive (CGRP-IR) axon innervation of mouse stomach

Immunohistochemistry revealed the morphology and distribution of nociceptor Calcitonin gene-related peptide (CGRP) immunoreactive in the muscular layers (longitudinal muscle, myenteric plexus, and circular muscle) of the mouse stomach.

80 Files

2.86 GB

41 Records

Duyen Nguyen updated on February 14, 2024

mouse, confocal microscopy, cgrp + More

Mapping of vagal sensory nerve populations and their brainstem projections in mice

This dataset contains confocal images of vagal ganglia and brainstem from TRPV1, Tac1, Pirt and 5HT3 Cre mice crossed with a reporter strain.

4,816 Files

8.34 GB

89 Records

Thomas Taylor-Clark updated on February 14, 2024

medulla, pa5, nts + More

Influence of vagus nerve stimulation on vagal and cardiac activity in freely moving pigs

This dataset maps the relationship between vagus nerve stimulation (VNS) parameters to their immediate neural and cardiac effects in 2 freely moving pigs.

24 Files

1.49 GB

8 Records

Oliver Armitage updated on February 14, 2024

evoked compound action potential, stimulation parameters, pig + More

A mathematical model for simulating the neural regulation of phasic contractions and slow waves in the distal stomach

An interactive oSPARC implementation

9 Files

107.02 KB

No Records

Omkar Athavale updated on February 13, 2024

mathematical model, electrical field stimulation, slow waves + More

Effects of manipulating epithelial cell-nerve signaling on anxiety-like behavior in mice

Elevated-plus maze data collected from animals with silenced/activated gut enterochromaffin cells

21 Files

194.6 KB

81 Records

Archana Venkataraman updated on February 9, 2024

mouse, mucosal afferents, elevated plus maze + More

Electromyogram recordings in mice during vagus nerve stimulation

Acute physiological data describing muscle activation during VNS at different burst patterns and frequencies. This includes raw EMG files and quantified outcomes.

2,214 Files

22.89 GB

13 Records

Nicole Pelot updated on February 8, 2024

vagus, emg, heart rate + More

Electrocardiogram recordings in mice during vagus nerve stimulation

Acute physiological data describing heart rate modulation during VNS at different burst patterns and frequencies. this includes raw ECG files and quantified outcomes.

2,238 Files

23.15 GB

13 Records

Nicole Pelot updated on February 8, 2024

vagus nerve, electrophysiology, dynamic range + More

Two-Color Diffuse In Vivo Flow Cytometer

Processed diffuse in vivo flow cytometry (DiFC) data for the validation of Two-Color DiFC. Including in vitro phantom data and mouse data.

18 Files

62.16 MB

No Records

Amber Williams updated on February 6, 2024

circulating tumor cells, metastasis, in vivo flow cytometry + More

Distribution and morphology of calcitonin gene-related peptide (CGRP) innervation in flat mounts of whole rat atria and ventricles

The sensory (nociceptive) innervation of the whole rat heart (including the atria and ventricles) was immunohistochemically labeled for CGRP. Moreover, high-quality images of the whole tissue were acquired at the single-cell/axon/varicosity resolution.

735 Files

536.29 GB

No Records

Kohlton Bendowski updated on January 13, 2024

calcitonin gene-related peptide, whole heart, vasculature + More

Sex differences in sympathetic gene expression and cardiac neurochemistry in Wistar Kyoto rats

Characterizes the transcriptome of both male and female stellate ganglia and to correlate that with catecholamine and acetylcholine content in the heart.

43 Files

29.94 MB

13 Records

Jeffrey Ardell updated on January 12, 2024

sparc, transcriptome, sympathetic + More

Quantitation of nodose neurons labelled by retrograde tracing from selective gastric mucosal and gastric muscle injection

Microinjection of fluorescent nanospheres into either the muscle or mucosal of the stomach in the corpus regions in rats labels distinct populations of nodose neurons

135 Files

62 GB

77 Records

Martin Stebbing updated on January 11, 2024

nodose, muscle, rat + More

RNAseq analysis of nodose neurons projecting to specific regions and tissue layers within the rat stomach

Vagal sensory neurons projecting to either the muscle or mucosal layers of the rat stomach in the fundus, corpus or antrum were identified using localized microinjections retrograde tracer, before being isolated and characterized using RNAseq.

1,275 Files

81.85 GB

No Records

Martin Stebbing updated on January 11, 2024

rat, nodose, rnaseq + More

Quantitation of nodose neurons labelled by retrograde tracing from selective injections into the gastric mucosa or muscle in the antrum and fundus

Microinjections of a non-diffusible retrograde tracer were made into the muscle layer or the mucosal layer of the rat stomach in either the antrum or the fundus region. Retrogradely labelled nodose neurons were studied using 3-D confocal microscopy.

211 Files

52.44 GB

No Records

Martin Stebbing updated on January 11, 2024

antrum, fundus, stomach + More

Synaptic components function and modulation characterized by GCaMP6f calcium imaging in cholinergic myenteric ganglion neurons

Synapses and their components on myenteric neurons assessed by GCaMP Ca2+ imaging

204 Files

365.55 GB

199 Records

Marthe Howard updated on January 11, 2024

myenteric, nicotinic, synapse + More

Find and access public scientific datasets.

Status

Tags

Targeting bladder function with network-specific epidural stimulation after chronic spinal cord injury

Long read sequencing of human dorsal root ganglia

Transcriptomic and neurochemical analysis of the stellate ganglia in mice highlights sex differences

Quantification of enteric ganglia in the three main regions of the rat stomach

Vagal preganglionic axons arborize in myenteric plexus into two patterns generating nitrergic and non-nitrergic postganglionic motor units

Vasculature in mouse colon and relationship with enteric nervous system glia and macrophages

Light microscopic analysis of synaptic input to neurons in the rat major pelvic ganglion

Transduction of systemically administered adeno-associated virus in the colonic enteric nervous system of adult mice

Substance P-immunoreactive axons in the antrum-pylorus-duodenum of mice

Excitation properties of computational models of unmyelinated peripheral axons

Intravenously injected AAV9 transduced interstitial cells of Cajal in mouse colon

Calcitonin gene-related peptide - immunoreactive (CGRP-IR) axon innervation of mouse stomach

Mapping of vagal sensory nerve populations and their brainstem projections in mice

Influence of vagus nerve stimulation on vagal and cardiac activity in freely moving pigs

A mathematical model for simulating the neural regulation of phasic contractions and slow waves in the distal stomach

Effects of manipulating epithelial cell-nerve signaling on anxiety-like behavior in mice

Electromyogram recordings in mice during vagus nerve stimulation

Electrocardiogram recordings in mice during vagus nerve stimulation

Two-Color Diffuse In Vivo Flow Cytometer

Distribution and morphology of calcitonin gene-related peptide (CGRP) innervation in flat mounts of whole rat atria and ventricles

Sex differences in sympathetic gene expression and cardiac neurochemistry in Wistar Kyoto rats

Quantitation of nodose neurons labelled by retrograde tracing from selective gastric mucosal and gastric muscle injection

RNAseq analysis of nodose neurons projecting to specific regions and tissue layers within the rat stomach

Quantitation of nodose neurons labelled by retrograde tracing from selective injections into the gastric mucosa or muscle in the antrum and fundus

Synaptic components function and modulation characterized by GCaMP6f calcium imaging in cholinergic myenteric ganglion neurons

Find and access public scientific datasets.

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