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Phrenic Nerve Stimulation Spinal Intact Rats

We are testing the hypothesis that activation of phrenic afferent neurons modulates contralateral phrenic motor output and blood pressure in the adult rat.
99 Files
93.7 GB
47 Records
CC-BY-4.0
David Fuller updated on June 15, 2021
phrenic motor output, phrenic nerve, respiratory bursting + More
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Influence of acute celiac branch of abdominal vagus nerve stimulation on colonic motility in anesthetized male Yucatan minipigs

Acute celiac branch of vagus nerve electrical stimulation; monitor colon manometry in all regions (proximal, transverse and distal) before, during and post stimulation.
206 Files
1.56 GB
45 Records
CC-BY-4.0
Muriel Larauche updated on June 14, 2021
pre-clinical, pelvic, electroceutical-therapy + More
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Influence of acute thoracolumbar root nerves electrical stimulation on colonic motility in anesthetized male Yucatan minipigs

Acute thoracolumbar nerve electrical stimulation; monitor colon manometry in all regions (proximal, transverse and distal) before, during and post stimulation.
87 Files
210.71 MB
20 Records
CC-BY-4.0
Muriel Larauche updated on June 14, 2021
pre-clinical, pelvic, electroceutical-therapy + More
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Generic rat heart scaffold

Annotated heart scaffold for rat available for registration of segmented neural anatomical-functional mapping of cardiac neural circuits.
40 Files
4.91 MB
5 Records
CC-BY-4.0
Richard Christie updated on June 9, 2021
coronary, cardiac zone, heart + More
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Generic pig heart scaffold

Annotated heart scaffold for pig available for registration of segmented neural anatomical-functional mapping of cardiac neural circuits.
41 Files
5.06 MB
5 Records
CC-BY-4.0
Richard Christie updated on June 9, 2021
coronary, pig, cardiac zone + More
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Generic human heart scaffold

Annotated heart scaffold for human available for registration of segmented neural anatomical-functional mapping of cardiac neural circuits.
41 Files
5.59 MB
5 Records
CC-BY-4.0
Richard Christie updated on June 9, 2021
coronary, human, cardiac zone + More
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In Vitro Imaging of Mechanosensitive Submucous Neurons in the Porcine Colon

This dataset is about electrophysiological experiment on porcine colonic submucosal enteric neurons. The neurons were challenged with 2 different mechanical stimuli (compression and stretch). Neuronal responses to the stimuli were recorded and analyzed.
73 Files
22.81 MB
115 Records
CC-BY-4.0
Gemma Mazzuoli-Weber updated on June 4, 2021
mechanosensitivity, voltage sensitive dye, ultrafast neuroimaging technique + More
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Chemogenetic Activation or Inhibition of Cholinergic or Nitrergic Myenteric Neurons of Mouse Colon

Contractile response to the chemogenetic activation or inhibition of distinct myenteric neuronal subsets
61 Files
166.81 MB
No Records
CC-BY-4.0
Thomas Gould updated on June 3, 2021
optogenetics, myenteric plexus, motility + More
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Rat whole-body with embedded organs

The generated body scaffold was fitted to data and the organ fiducial markers were embedded in the rat whole-body. The landmarks were obtained from image data and also were defined in the body scaffold.
40 Files
23.46 MB
No Records
CC-BY-4.0
Elias Soltani updated on June 2, 2021
rat, abdomen, diaphragm + More
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Generic rat lung scaffold

Annotated lung scaffold for rat available for registration of segmented neural anatomical-functional mapping of pulmonary neural circuits.
29 Files
2.71 MB
No Records
CC-BY-4.0
Arti Sukasem updated on June 2, 2021
lung, rat, scaffold
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Generic rat bladder scaffold

Annotated bladder scaffold for rat available for registration of segmented neural anatomical-functional mapping of LUT neural circuits.
34 Files
2.36 MB
5 Records
CC-BY-4.0
Zohreh Ekhlasi updated on June 2, 2021
urinary bladder, urethra, body of the bladder + More
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Generic mouse lung scaffold

Annotated lung scaffold for mouse available for registration of segmented neural anatomical-functional mapping of pulmonary neural circuits.
37 Files
2.69 MB
5 Records
CC-BY-4.0
Arti Sukasem updated on June 2, 2021
lung, mouse
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Generic human lung scaffold

Annotated lung scaffold for human available for registration of segmented neural anatomical-functional mapping of pulmonary neural circuits.
37 Files
2.44 MB
5 Records
CC-BY-4.0
Arti Sukasem updated on June 2, 2021
lung, human
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Effects of cystotomy on the feline urinary bladder

Cystometry and imaging data for the evaluation of the cat bladder before and after cystotomy.
2,957 Files
7.04 GB
39 Records
CC-BY-4.0
Dataset will be released on May 19, 2022
cat, pressure, bladder + More
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Influence of direct colon tissue electrical stimulation on colonic motility in anesthetized male Yucatan minipig

Direct proximal colon, transverse colon and colorectum wall electrical stimulation; monitor colon wall bio-impedance and colon manometry in all regions (proximal, transverse and distal) before, during and post stimulation.
182 Files
64.09 GB
45 Records
CC-BY-4.0

Sponsored by

NIH SPARC Program

Yvette Tache updated on June 1, 2021
autonomic, pelvic, gastrointestinal + More
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Test case for physiological data visualisation

Dataset to investigate annotations required for visualisation of physiological data on the portal
22 Files
31.04 MB
No Records
CC-BY-4.0
Mabelle Lin updated on June 1, 2021
physiological data, time series
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Generic human bladder scaffold

Annotated bladder scaffold for human available for registration of segmented neural anatomical-functional mapping of LUT neural circuits.
25 Files
1.83 MB
No Records
CC-BY-4.0
Zohreh Ekhlasi updated on June 1, 2021
human, neck of the bladder, body of the bladder + More
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Generic cat bladder scaffold

Annotated bladder scaffold for cat available for registration of segmented neural anatomical-functional mapping of LUT neural circuits.
32 Files
2.31 MB
5 Records
CC-BY-4.0
Zohreh Ekhlasi updated on June 1, 2021
cat, neck of the bladder, body of the bladder + More
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Optogenetic Stimulation Prevents Lipopolysaccharide Induced TNFa Production

Animal study (C57BL/6J background transgenic mice) to determine the involvement of the superior mesenteric ganglion in the cholinergic anti-inflammatory pathway using optogenetic activation or blockade.
38 Files
489.03 KB
134 Records
CC-BY-4.0
Jessica Sladek updated on May 18, 2021
caip, smg, neuronal circuit
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Jupyterlab Exploration of Computational Models of Unmyelinated Peripheral Axons

Example JupyterLab environment used to compile, run and display results of neural computational models, based on a SPARC dataset (https://doi.org/10.26275/iiwv-k07f)
6 Files
25.48 KB
No Records
MIT
Katie Zhuang updated on May 16, 2021
jupyterlab, neuron, computational model + More
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Triaxial mechanical testing of dog colon segments

Measurement data related to the mechanical testing of dog colon samples under triaxial (inflation, extension, torsion) loading.
46 Files
3.1 MB
29 Records
CC-BY-4.0
Dataset will be released on September 1, 2021
force, inflation, pressure + More
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TRAP-SEQ (Translating Ribosome Affinity Purification followed by RNA sequencing) of iBAT-related ganglia from 7-day cold and warm treated mice

Molecular-genetic techniques in the autonomic nervous system: Projection-specific tracing and ribosomal RNA pulldown
51 Files
22.68 GB
13 Records
CC-BY-4.0
Heike Muenzberg updated on May 13, 2021
gene expression, ganglion, cold treatment + More
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RNA sequencing reveals novel transcripts from sympathetic stellate ganglia during cardiac sympathetic hyperactivity in rats

Stellate ganglia of 15-16 week old Wistar and Spontaneously Hypertensive Rats were analyzed by: RNA-sequencing, differential analysis, and gene ontology analysis. Data were analyzed by a pipeline consisting of Salmon, DESeq2, and clusterprofiler.
27 Files
3.3 MB
25 Records
CC-BY-4.0
scott john updated on May 13, 2021
differential expression, rna-sequencing, stellate ganglia + More
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Tool for uploading files to Blackfynn

Upload_bfynn aids with file uploads to Blackfynn. Users create a csv file with folders and names that meet the BIDS-like standards and lists the sources of files to be uploaded into these folders. Local filenames and folder structures are not changed.
100 Files
37.14 MB
6 Records
GPL-3.0
Kendall Morris updated on May 12, 2021
software, neural circuits, spike trains + More
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Acquisition of single neurons and regional neuronal samples from the porcine Right Atrial Ganglionic Plexus (RAGP) through Laser Capture Microdissection

Transcriptional Diversity of Single Neurons in the Porcine RAGP.High throughput qPCR data for over 400 single neurons assayed for hundreds of genes across 4 pig RAGP
11,073 Files
7.32 GB
2 Records
CC-BY-4.0
Alison Moss updated on May 14, 2021
sparc, ragp, lcm + More
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